關於 chimeric antigen receptor therapy ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. CAR T-Cell Therapy - Dana-Farber Cancer Institute | Boston, MA

Chimeric antigen receptor, or CAR T-cell therapy, is a new form of immunotherapy that uses specially altered T cells to more specifically target cancer ...

#12. CAR T-Cell Therapy - Cincinnati Children's Hospital

CAR T-cell therapy (also called chimeric antigen receptor T-cell therapy) is a type of cancer treatment. It uses infection-fighting cells in the immune ...

#13. Side-effect management of chimeric antigen receptor (CAR) T ...

Due to the nature of CAR T cells as living drugs, they display a unique toxicity profile. As CAR T-cell therapy is extending towards other diseases and being ...

#14. An introduction to chimeric antigen receptor (CAR) T‐cell ...

Chimeric antigen receptor (CAR) T-cell therapy represents a major advancement in ...

#15. CAR-T Cell Therapy Program - Mayo Clinic

To make CAR-T cells, the collected T cells are genetically treated in the lab to produce special receptors called chimeric antigen receptors ...

#16. (CAR) T-cell therapy - Moffitt Cancer Center

Chimeric antigen receptor therapy (CAR T cell therapy) is an immunological treatment that uses the body's own immune system to destroy cancerous cells.

#17. Challenges and Advances in Chimeric Antigen Receptor ...

So far, CAR therapy has been used more frequently in B-cell mediated cancers due to unique challenges posed by patients with acute myeloid leukemia (AML) and ...

#18. CAR T-cell therapy - Cancer Research UK

CAR stands for chimeric antigen receptor. These CAR T-cells are designed to recognise and target a specific protein on the cancer cells.

#19. Posttransplant chimeric antigen receptor therapy | Blood

Originally conceived as a hematopoietic rescue following intensive chemotherapy, 1 allogeneic hematopoietic cell transplantation (allo-HCT) eventually evolved as ...

#20. CD19-targeted chimeric antigen receptor T-cell therapy for ...

CD19-targeted chimeric antigen receptor T-cell therapy for CNS relapsed or refractory acute lymphocytic leukaemia: a post-hoc analysis of ...

#21. Chimeric Antigen Receptor T-cell Therapy – Clinical Guideline

The cells are sent to a centralized manufacturing facility where they are genetically modified to produce specific chimeric antigen receptors ...

#22. Considerations for the Development of Chimeric Antigen ...

Chimeric antigen receptor (CAR) T cell products are human gene therapy products in which the T cell specificity is genetically modified to ...

#23. Chimeric antigen receptor T cells: a novel therapy for solid ...

由 S Yu 著作 · 2017 · 被引用 245 次 — The chimeric antigen receptor T (CAR-T) cell therapy is a newly developed adoptive antitumor treatment. Theoretically, CAR-T cells can ...

#24. Chimeric antigen receptor (CAR) T therapies for the treatment ...

Genetic engineering of novel receptors – now known as Chimeric Antigen Receptors (CAR) – can both recognize cancer-associated antigens and provide T cell ...

#25. Engineering and Design of Chimeric Antigen Receptors

T cells engineered with chimeric antigen receptors (CARs) have ... to CAR T cell therapies.3,10,16 Fourth, in order to be effective in solid.

#26. Cardiotoxicity from chimeric antigen receptor-T cell therapy for ...

Chimeric antigen receptor (CAR)-T cell therapy is the next revolutionary advance in cancer therapy. By using ex vivo engineered T cells to ...

#27. Chimeric antigen receptor signaling: Functional ... - Science

Chimeric antigen receptor (CAR) T cell therapy has transformed the care of refractory B cell malignancies and holds tremendous promise for many aggressive ...

#28. Chimeric Antigen Receptor Therapy for Cancer

Chimeric antigen receptors (CARs) have a single-chain antibody fragment (scFv), expressed in ... CURRENT STATUS OF CHIMERIC ANTIGEN RECEPTOR T CELL THERAPY.

#29. CAR-T Therapy - NHS England

What is Chimeric Antigen Receptors Cell Therapy (CAR-T)? ... CAR-T is a highly complex and innovative new treatment. CAR-T is a type of immunotherapy which ...

#30. Chimeric Antigen Receptor T-Cell Therapy Clinical Results in...

Chimeric antigen receptor (CAR)-modified T-cell therapy has revolutionized the care of patients with relapsed and refractory B-cell acute lymphoblastic ...

#31. Chimeric Antigen Receptor T-Cell Therapies for Cancer

Promising Chimeric Antigen Receptors for Non-B-Cell Hematological Malignancies, Pediatric Solid Tumors, and Carcinomas · 12. CAR T-Cell Therapy for CNS ...

#32. NCD - Chimeric Antigen Receptor (CAR) T-cell Therapy - CMS

B-cells generate and release antibodies to fight infection, especially bacterial infections, while T-cells employ a number of other mechanisms to fight abnormal ...

#33. best practice recommendations of the European Society for ...

Patient eligibility for chimeric antigen receptor T-cell therapy. The decision to treat a patient with CAR T cells therapy should be made collectively at a ...

#34. Chimeric Antigen Receptor T-Cell Therapy: A Beacon of Hope ...

Chimeric antigen receptor T-cell (CAR-T) therapy is a newer treatment methodology approved by the Food and Drug Administration (FDA).

#35. CAR T Cell Therapy for Children, Teens, and Young Adults

Chimeric antigen receptor (CAR) T cell therapy is a type of therapy that uses your immune system (immunotherapy). Your immune system's first job is to help ...

#36. Chimeric Antigen Receptor T-Cell Therapies for Cancer

From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a ...

#37. Influence of patient characteristics on chimeric antigen ...

CD19-specific chimeric antigen receptor T cell (CD19 CAR T) therapy has shown high remission rates in patients with refractory/relapsed ...

#38. Chimeric Antigen Receptor Therapy | Cincinnati Children's

One of the latest discoveries in cancer treatment is called Chimeric Antigen Receptor T-cell therapy, or CAR T-cell therapy.

#39. CD19 Chimeric Antigen Receptor Therapy for Refractory ...

PURPOSEAnti-CD19–directed chimeric antigen receptor (CAR) T-cell therapy has had a resounding effect on the treatment of ...

#40. How Does CAR T-Cell Therapy Work in Treating Cancer?

Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy that modifies a person with cancer's immune system so it is more ...

#41. CAR T Cell Therapy for Cancer - City of Hope

CAR T cell therapy — chimeric antigen receptor — is the central component of a host of promising new cancer clinical trials and treatments currently ...

#42. Allogeneic Chimeric Antigen Receptor Therapy in Lymphoma

Chimeric antigen receptor T cell (CAR-T) therapy has been transformative for the treatment of relapsed/refractory (R/R) large B cell lymphoma ( ...

#43. Chimeric Antigen Receptor T Cells: A Race to Revolutionize ...

For years, cancer treatment was dominated by chemotherapy, radiation therapy, and stem cell transplantation. New insights into genetic ...

#44. Chimeric Antigen Receptor (CAR) T-cell Therapy

Chimeric Antigen Receptor (CAR) T-cell Therapy is a form of immunotherapy where T-cells are taken from the patient's blood and modified in a laboratory ...

#45. The curative potential of chimeric antigen receptor T-cell ...

However, these adoptive T-cell therapies do not change the mechanisms of the immune response. Cancerous cells can evade immune attack and dampen immune ...

#46. Prospects to improve chimeric antigen receptor T-cell therapy ...

Adoptive transfer of patient-derived T-cells engineered with a chimeric antigen receptor (CAR) targeting the pan-B-cell marker CD19 has led ...

#47. Critical Care Management of Chimeric Antigen Receptor T ...

Figure 1. A critical care view of CAR (chimeric antigen receptor) T-cell therapy. CART = chimeric antigen receptor T cell; CRS = cytokine release syndrome.

#48. Chimeric Antigen Receptor T Cell Therapy

Chimeric Antigen Receptor T Cell Therapy: Challenges to Bench-to-Bedside Efficacy. Shivani Srivastava and Stanley R. Riddell.

#49. Advances Of Chimeric Antigen Receptor T Cell Therapy In ...

Chimeric antigen receptor T (CAR-T) cell therapy, as a representative of adoptive T cell immunotherapy, plays an important role in cancer ...

#50. CAR T Cell Therapy | MD Anderson Cancer Center

Chimeric antigen receptor (CAR) T cell therapy is a type of cellular immunotherapy that changes T cells so they are able to recognize and attack cancer.

#51. Chimeric antigen receptor T (CAR T) cells - Kidney International

Chimeric antigen receptor T (CAR T) cells: another cancer therapy with potential applications in kidney disease and transplantation?

#52. Chimeric Antigen Receptor Therapies - ResearchGate

Download Citation | On Jan 1, 2020, Lisa Senzel and others published Chimeric Antigen Receptor Therapies | Find, read and cite all the research you need on ...

#53. Chimeric Antigen Receptor Therapy for B-cell Malignancies

J Cancer 2011; 2:331-332. doi:10.7150/jca.2.331 This volume. Short Report. Chimeric Antigen Receptor Therapy for B-cell Malignancies.

#54. chimeric antigen receptor T-cell therapy | medicine | Britannica

Other articles where chimeric antigen receptor T-cell therapy is discussed: cancer: Immunotherapy: …similar T-cell therapy, known as chimeric antigen ...

#55. FDA-approved CAR T-cell Therapies | UPMC Hillman

Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy that uses a patient's own genetically modified T cells to find and kill cancer.

#56. Chimeric Antigen Receptor T Cell Therapy

Chimeric antigen receptor T cell (CAR T) therapy has been integrated into treatment algorithms for acute leukemia, lymphoma, and, most recently, ...

#57. EURopean Endeavour for Chimeric Antigen Receptor Therapies

Adoptive immunotherapy with T cells genetically modified with a tumour-reactive chimeric antigen receptor (CAR) is an innovative therapeutic ...

#58. Chimeric Antigen Receptor T-Cell Therapy in - JNCCN

Chimeric antigen receptor (CAR) T cells are genetically engineered cells that represent a novel class of cancer immunotherapy. The development of adoptive ...

#59. [PDF] Chimeric antigen receptor therapy for cancer.

A review of the CAR construct, early and ongoing CAR trials in B cell malignancies, the presentation, monitoring, and management of major ...

#60. Therapeutic applications of engineered chimeric antigen ...

Chimeric antigen receptor -T cells are sometimes used to develop immune-checkpoint blockers such PD-1 scFvs and PD-L1 antibody, and the ability ...

#61. MCARH109 Chimeric Antigen Receptor (CAR) Modified T ...

Patients who have not received any myeloma therapy for the preceding 6 months, except if the last myeloma therapy was a CAR T cell therapy. At ...

#62. Paving the Way Towards Universal Chimeric Antigen ...

Chimeric antigen receptor (CAR) therapy has been proved effective in a stream of clinical trials, especially in hematologic malignancies.

#63. The Promise of Chimeric Antigen Receptor T-Cell Therapy

Chimeric antigen receptors (CARs) are engineered molecules that can be introduced into T cells to enable them to target specific tumor ...

#64. Chimeric Antigen Receptor Therapy for Leukemia ... - BCBSND

Chimeric antigen receptor (CAR) T-cells are genetically engineered cells that represent a novel class of cancer immunotherapy. In general, the process of ...

#65. Medical Policy - Chimeric Antigen Receptor Therapy for ...

Prior Authorization Request Form: Chimeric Antigen Receptor Therapy for Hematologic. Malignancies. This form must be completed and faxed to: Medical and ...

#66. Gated chimeric antigen receptor T-cells: the next logical step ...

However, a key hurdle in the widespread use of adoptive T-cell therapy is the paucity of antigens exclusively expressed by tumors. In a recent ...

#67. Expression of chimeric antigen receptor therapy targets in ...

Chimeric antigen receptor (CAR)-engineered cell therapy, which leverages genetically modified immune cells to generate a tailored immune ...

#68. Chimeric Antigen Receptor (CAR) T-cell Therapy

CAR T-cell therapy is a type of immunotherapy called “adoptive T-cell immunotherapy.” Immunotherapy uses a person's own immune cells to fight cancer. CAR T-cell ...

#69. Cancer Immunotherapy with Chimeric Antigen Receptor (CAR ...

Chimeric antigen receptor (CAR) T-cell therapy is an emerging cancer treatment modality in which the patients' own immune cells are ...

#70. Application of Chimeric Antigen Receptor T Cells in ... - Hindawi

However, T cell exhaustion might lead to the possibility of immune escape of hematological malignancies. Adoptive cell therapy (ACT) with chimeric antigen ...

#71. CAR T-Cell Therapy for Cancer - OHSU

T cells are lymphocytes — a type of white blood cell that fights infection as part of the immune system. CAR (chimeric antigen receptor) is a new kind of ...

#72. Chimeric Antigen Receptor Therapy for Cancer

T cell therapies for the treatment of cancer uti- lizing chimeric antigen receptors (CARs). History and Rationale for Adoptive.

#73. The roles of T cell competition and stochastic extinction events ...

Chimeric antigen receptor (CAR) T cell therapy is a remarkably effective immunotherapy that relies on in vivo expansion of engineered CAR T ...

#74. Chimeric Antigen Receptor (CAR) T-cell therapy

Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy that uses a person's own immune system to try to destroy lymphoma cells.

#75. Chimeric Antigen Receptor (CAR) T-Cell Therapy for Thoracic ...

Chimeric Antigen Receptor (CAR) T-Cell Therapy for. Thoracic Malignancies ... therapy for solid tumors and present strategies that have.

#76. CAR T-CELL THERAPY | Peter MacCallum Cancer Centre

CAR T-cell therapy is a new form of immunotherapy that uses specially altered ... structures called chimeric antigen receptors (CARs) on their surface.

#77. Chimeric Antigen Receptor T Cell Therapy and the Kidney

This therapy requires drawing of blood from patients and separating out T cells. After that, using a disarmed virus, the T cells are genetically ...

#78. Chimeric Antigen Receptor T-Cell Therapies for C

From patient referral to post-therapy management, Chimeric Antigen Receptor (CAR) T-Cell Therapies for Cancer: A Practical Guide presents a comprehensive ...

#79. Challenges and Prospects of Chimeric Antigen Receptor T ...

So far, chimeric antigen receptor (CAR) T-cell therapy has not shown significant activity in patients with metastatic prostate cancer (PCa).

#80. Chimeric Antigen Receptor (CAR) T-Cell Therapy

Chimeric Antigen Receptor (CAR) T-Cell Therapy · The · Lymphocytes, a subtype of · Immunotherapy · Immune cells or antibodies can be produced in the laboratory ...

#81. Chimeric Antigen Receptor T-Cell Therapy Article - StatPearls

Chimeric antigen receptors (CARs) are recombinant receptors for antigens which redirect the specificity and function of T lymphocytes and/or ...

#82. Chimeric Antigen Receptors for T-Cell Based Therapy | Springer ...

Chimeric Antigen Receptors for T-Cell Based Therapy. Authors: Eleanor J. Cheadle 3 , 5 ,. Vicky Sheard 1 ,. Andreas A. Hombach 4 ,. Markus Chmielewski 4.

#83. Chimeric antigen receptor (CAR) T cell therapy - OAText

Chimeric antigen receptor (CAR) T cell therapy is a promising new immunotherapy that reprograms patient T lymphocytes to specifically recognize and kill ...

#84. Podcast: CAR T-cell therapy for people with diffuse large B ...

A new Cochrane Review from September 2021 looks at the evidence on the effects of one treatment, chimeric antigen receptor (CAR) T-cell therapy for people ...

#85. Chimeric Antigen Receptor T-Cell (CAR-T) Therapy

In 2017, the FDA approved the first ever gene immunotherapy to treat cancer. It is called chimeric antigen receptor T-cell therapy or CAR-T, for short. The one- ...

#86. A Primer on Chimeric Antigen Receptor T-cell Therapy

Chimeric antigen receptor T-cell (CAR-T) technology has shown great promise in both clinical and preclinical models in mediating potent and ...

#87. Chimeric Antigen Receptor T-Cell Therapy: How it Works

Chimeric Antigen Receptor T-Cell Therapy: How it Works ... The immune system is the body's defense against infection and cancer. It is made up of ...

#88. The Promise of CAR T Cell Therapy in 2019 and Beyond

Chimeric antigen receptor (CAR) T cell therapy represents an incredibly promising cellular immunotherapy approach for treating cancer that ...

#89. CAR T-Cell Therapy - Philadelphia - Fox Chase Cancer Center

Chimeric antigen receptor (CAR) T-cell therapy is a type of immunotherapy that reprograms a patient's own T cells to recognize and destroy cancer cells.

#90. CAR T cell principles - Carl DeSelm Lab

Chimeric antigen receptor T cells for sustained remissions in leukemia. N Engl J Med. 2014. Park JH, et al. Long-Term Follow-up of CD19 CAR Therapy in Acute ...

#91. The World's First CAR-T Therapy Released the Latest Data

February 9, 2018 Chimeric Antigen Receptor Research, ... In simple terms, CAR-T therapy involves the isolation of T cells from a patient and ...

#92. Researchers create a single-cell framework to potentially ...

... a method that could improve CAR T-cell therapies by identifying the ... of cancer-killing chimeric antigen receptor (CAR) T cells can, ...

#93. Chimeric engulfment receptor (CER) T-cell therapy

CER T-cells behave like chimeric antigen receptor (CAR) T-cells but can enhance antigen presentation of T cells, mediating tumor clearance and inducing a ...

#94. CAR T cell therapy for multiple myeloma: How does it work?

An emerging form of treatment is chimeric antigen receptor (CAR) T cell therapy. Multiple myeloma is a type of plasma cell neoplasm, ...

#95. What is CAR-T Therapy? - Metastatic Breast Cancer Trial Talk

The blood cells are removed from the patient and then modified with chimeric antigen receptors (CARs) so they can attack specific proteins.

#96. CAR T Cell Therapy for The Treatment of Cancer

These proteins are called chimeric antigen receptors (CARs). The CARs are important because they enable the T cells to recognize and bind to ...

#97. The Promise of CAR T-Cell Therapy: Q+A with Ran Reshef, MD

Among these is a promising type of treatment called chimeric antigen receptor (CAR) T-cell therapy, which re-engineers a patient's white ...