Saw a screen cap of a good read on IG that's worthy to share. Here is what is from @foodgazerrr 's reads and that screen makes me happy to know that someone also cares about food knowledge other than just the taste of the food.
We are very blessed to have no food shortage and nowadays people got carried away with that easily, because of social media. It's come to a point where we are only looking at what's good where and what's newly open where. Being the first to try the food and being a part of having experienced the latest food trend becomes an utmost priority so to be able to flaunt on social media. I never am ever been thrilled with such instead, I'm always keen with how food becomes what it is in current modern dates. Learning about the history and evolution of food is of a greater meaning to understand and learn about roots of humanity and culture from ancient time when food formed into becoming than just a source of fuel.
Don't get me wrong, I didn't mean seeking best and trendiest food being a wrong thing to do. I am just saying that understanding it's origin is equally as important.
Seeking where the best foods are normal and reasonable because we want only the best and what's best of the value for money that we are spending on our food. Chasing where new eatery is opening is part of evolution because we want to fill ourselves with knowledge and latest trend. But blindly doing so could neglect the importance of knowing your food origin and that's loosing heritage and culture along the way . I bet 8 out of 10 people don't care what's the history of food. (I know... Cause my posting insight would tell me a stat of the type of contents people engaged with and such philosophy doesn't appeal to 8 out of 10 people, hahaah....)
I do hope that constant reminder of such would be helpful because I really do want to have a balance of posting what's helpful and what's necessary, regardless if it is best for my social media.
#foodeverywhere #sycookiesinpire #humanitarinism
no cap meaning 在 台灣光鹽生物科技學苑 Facebook 的最讚貼文
<生醫新聞>Cyclacel臨床三期的急性骨髓性白血病藥物在關鍵研究中失敗
#AcuteMyeloidLeukemia #FailedTrials #ClinicalResearch #Cyclacel #Decitabine #Sapacitabine #FDA
Cyclacel Pharmaceuticals has been taught the meaning of futility. Two years after an independent data monitoring board told Cyclacel its phase 3 acute myeloid leukemia (AML) trial was destined to fail, the ever-optimistic biotech has reported its drug sapacitabine was unable to better the active control in terms of overall survival.
The top-line data confirm an outcome that looked likely from the minute independent advisers told Cyclacel the study had failed an interim futility review in December 2014. By then, the phase 3 trial had chalked up 247 of the 424 patient deaths needed to trigger the end of the study. But, with the review finding no safety issues that would force Cyclacel to shutter the study, the NJ-based biotech pushed ahead regardless.
A little more than two years later, Cyclacel has learnt sapacitabine is no better at improving overall survival in elderly patients with AML than decitabine, an Otsuka drug FDA rejected in the indication in 2012 on the basis that it also failed to outperform the control arm in its own study. Decitabine, sold under the name Dacogen as a treatment for myelodysplastic syndromes, is used off-label in elderly AML patients because of the dearth of options in this population.
When combined with the performance of sapacitabine against some secondary endpoints, the lack of options for elderly patients with AML who cannot or will not undergo chemotherapy has given Cyclacel encouragement to continue seeking a way forward for the drug.
“We plan to discuss the data with European and U.S. regulatory authorities once subgroup analyses are completed over the next few months and will report our further plans as they develop,” CEO Spiro Rombotis said in a statement.
Rombotis and the chair of the phase 3, MD Anderson’s Hagop Kantarjian M.D., picked out the data on complete remission and safety as cause for optimism. Kantarjian, a critic of FDA’s decision to reject decitabine in AML, called the improved rate of complete remission “remarkable.” Cyclacel said the safety of the two arms was similar.
While Rombotis and Kantarjian see the data as suggesting it is still too early to write off sapacitabine, investors were less optimistic. Cyclacel dropped 30% in premarket trading, adding further woes to a stock that is down 99% on the highs it hit a decade ago. The company’s market cap prior to news of the latest setback stood at $24 million.
資料來源:http://www.fiercebiotech.com/…/cyclacel-aml-drug-fails-phas…
no cap meaning 在 陳少寶 Facebook 的最佳貼文
自從4月份弟一個星期一,6號開始,我已經在新城數碼音樂台早上 10:00 轉播左11場,我認定嘅搖擺音樂經典時刻 (Rock's Historial Moments) 演唱會。睇番、聽番都好安慰,正如我一直都講,我一生是上帝差遣我來侍奉音樂,所以是無比興奮,樂在其中!!!!
Re-cap 一下:
01. Cream (4月6號+13號) - Reunion Concert (Eric Clapton,Jack Bruce,Ginger Baker.After 35 years disband,Jack Bruce died 2014)
02. George Harrison Memorial Concert (4月20號) - Jeff Lynn,Tom Petty,Eric Clapton,Ringo Starr,Billy Preston,Paul McCartney,The Shankar Family and Dhani,George's son.Mr.Harrison died 2001)
03. Santana (4月27號) - Lotus concert live in Japan (Carlos and the band at the peak of their career disbanded after this tour....back with hugh success in the year 1999 with album Supernatural)
04. Paul McCartney & Wings (5月4號 + 5月11號) - Wings Over America (First tour with band Wings in America after Beatles split up in 1970)
05. Yes (5月18號 + 25號) - Yessongs Tour (Fisrt offical tour for Progress Rock band Yes,mainly promote the album Close To The Edge,legendary drummer Bill Bruford left in the middle of the tour,Alan White stepped in)
06. Deep Purple (6月1號) - Live In Japan (the best line up of the group Ian Gillan,Roger Glover,Ritch Blackmore,Ian Paice and Jon Lord.The biggest selling live album of Metal Rock band,the only offical live recording of this line up.Also the very first time Japan known world wide as a heavy metal country!!!Jon Lord passed away in 2012)
07. Jackson Browne (6月8號) - Running On Empty tour (Jackson mixed live and hotel takes of recordings into this 5 million sales live album,marked the first song writer hit top of the chart with a "In Concert",also re-write the meaning of "Live Album",by putting in no old materials.What a record!!??)
08. Joe Cocker (6月15號 + 22號) - Mad Dog and The Englishman (Literally the first Rocker that does well known covers,and,turned them into hits again.With A Little Help From My Friends hit big in Woodstock.Joe went to America formed The Mad Dog and put out this live recording,band leader and composer as well as muti-instrumentalist Leon Russell and his band members captured the so call "NEW" blue eyed soul and rock,not only a classic performance,it's an one off.The Mad Dog later on became the most used band for acts like Eric Clapton,Delany & Bonnie,Ringo Starr,Bob Dylan and the Rolling Stones.the Englishman died in 2014)
7月份我選播咗Led Zeppelin 2007年倫敦O2 Arena的Celebration Day同兩場Rolling Stones嘅經典演唱會1969,結他手Brian Jones去世,弟一場在美國嘅concert與及45年之後重返Hyde Park的十萬人演出,the band is still in top form!!!
記住逢星期一新城數碼音樂台早上 10:00,Rock's Historial Moments,此情不再嘅 ROCK PERFORMANCE!!!!
no cap meaning 在 No Cap ? 沒帽子? No cap 意思就是no... | Facebook 的推薦與評價
No Cap ? 沒帽子? No cap 意思就是no lie! 中文有點像「沒在跟你說謊、認真的、沒在開玩笑」 舉例: I am so tired. I can sleep rn, no cap! 我真的好累, ... ... <看更多>