關於 gm-csf function ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. GM-CSF as a therapeutic target in autoimmune diseases

In the intestine, GM-CSF contributes to mucosal barrier function and resistance to bacterial translocation by promoting the recruitment and ...

#12. Role of GM-CSF in regulating metabolism and mitochondrial ...

Granulocyte-macrophage colony-stimulating factor (GM-CSF) exerts pleiotropic effects on macrophages and is required for self-renewal but the ...

#13. Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory ...

In contrast to the role of GM-CSF as a pro-inflammatory cytokine, recent studies have described GM-CSF as a cytokine involved indirectly in the ...

#14. GM-CSF: A Promising Target in Inflammation and Autoimmunity

While GM-CSF appears to be dispensable for steady state myeloid cell development in vivo, GM-CSF directly regulates the differentiation of liver ...

#15. Defining GM-CSF– and Macrophage-CSF–Dependent ...

GM -CSF–treated bone marrow cells, in contrast, give rise to cells used ... function of these CSFs in human macrophage biology and pathology, ...

#16. GM-CSF Assay - Quanterix

GM -CSF functions as a white blood cell growth factor which stimulates stem cells to produce granulocytes and monocytes. It is used clinically to treat ...

#17. GM-CSF Antibody, Functional Grade (16-7331-81)

Invitrogen Anti-GM-CSF Monoclonal (MP1-22E9), eBioscience™, Catalog # 16-7331-81. Tested in ELISA (ELISA), Neutralization (Neu) and Functional assay (FN) ...

#18. Role of GM-CSF in a mouse model of experimental ...

GM -CSF serves as a significant activating and differentiation factor for immune cells and is essential for both innate and adaptive immunity (5) ...

#19. An update on GM-CSF and its potential role in melanoma ...

The GM-CSF designation derived from its ability to stimulate mouse bone marrow cell proliferation in vitro, and to generate colonies of ...

#20. Reprogramming of Monocytes by GM-CSF Contributes to ...

To this end, we chose an unbiased but comprehensive approach taking all potential functions of GM-CSF–activated monocytes (GMaMs) into account (gene expression, ...

#21. GM-CSF/CSF2 Protein Overview: Sequence, Structure ...

Know comprehensive GM-CSF/CSF2 protein information including protein sequence, molecular weight, theoretical pI, structure, function and protein ...

#22. Current status of granulocyte–macrophage colony-stimulating ...

GM -CSF plays a critical role in development and maturation of dendritic cells (DCs) and proliferation and activation of T cells, linking the innate and ...

#23. Opposite immune functions of GM-CSF administered as ...

GM -CSF functions are mediated by binding to a high-affinity receptor composed by a GM-CSF-specific α chain and, for human cells, by a β chain which is shared ...

#24. Characterisation of the expression and function of the GM ...

PDF | The granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine able to regulate a variety of cell functions including.

#25. Granulocyte-macrophage colony-stimulating factor/GM-CSF is ...

GM -CSF along with STAT proteins activates macrophages to impede fungal survival. They deprive the cells of free zinc and increase the reactive oxygen species ...

#26. GM-CSF and the role of myeloid regulatory cells in the ...

colony-stimulating factor (GM-CSF) exerts beneficial effects on intestinal inflammation and promotes ... function, GM-CSF has been proposed to be essential.

#27. Mouse GM-CSF

GM -CSF promotes immune system development and regulates neutrophil function during infection. Human and mouse GM-CSF show no cross-reactivity. [bulk_variations ...

#28. Mechanism of Action of A Human Granulopoietin - Gm-Csf

Granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates the ... required for function of the alpha and beta subunits of the GM-CSF receptor.

#29. Dual Role of GM-CSF as a Pro-Inflammatory and a Regulatory ...

Granulocyte macrophage colony stimulating factor (GM-CSF) is generally recognized as an inflammatory cytokine. Its inflammatory activity is primarily due ...

#30. A Review of GM-CSF Therapy in Sepsis : Medicine

Granulocyte-macrophage colony stimulating factor (GM-CSF), a naturally occurring cytokine that stimulates production and antibacterial function of neutrophils ...

#31. GMEssential Role of GM-CSF-Dependent Macrophages in ...

This review discusses recent findings about the role of human GMCSF-dependent macrophages in autoimmunity and inflammation. Induction of human GM-CSF-dependent ...

#32. GM-CSF Protein Human His Tag | Molgramostin - Prospec Bio

GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found ...

#33. Nontransformed, GM-CSF–dependent macrophage lines are ...

Macrophages are diverse cell types in the first line of antimicrobial defense. Only a limited number of primary mouse models exist to study their function. Bone ...

#34. Cytokine storm release syndrome and the prospects for ...

GM -CSF is a complex cytokine and a member of the colony-stimulating superfamily. While it does have a role as a growth factor for myeloid cells, ...

#35. The Pleiotropic Effects of the GM-CSF Rheostat on Myeloid ...

Keywords: GM-CSF, macrophages, dendritic cells, differentiation, function. INTRODUCTION. The Granulocyte Macrophage-Colony Stimulating ...

#36. Identification of a Non-Growth Factor Role for GM-CSF in ...

Rationale:Granulocyte macrophage colony-stimulating factor (GM-CSF, Csf2) is a growth factor for myeloid-lineage cells that has been ...

#37. InVivoMAb anti-human GM-CSF - Bio X Cell

To investigate the role of ORAI1 in proinflammatory Th1 and Th17 cells and autoimmune diseases, we genetically and pharmacologically modulated ORAI1 function.

#38. Combined GM-CSF treatment and M-CSF inhibition of tumor ...

Abstract. Macrophages demonstrate plasticity, and tumor- associated macrophages (TAM) can function as immuno- suppressive cells in the tumor ...

#39. Effects of granulocyte-macrophage colony-stimulating factor (GM ...

Effects of granulocyte-macrophage colony-stimulating factor (GM-CSF) on neutrophil kinetics and function in normal human volunteers. Publication Type, Journal ...

#40. Definition of granulocyte-macrophage colony-stimulating factor

It is a cytokine that is a type of hematopoietic (blood-forming) agent. Also called GM-CSF and sargramostim. Search NCI's Dictionary of Cancer Terms. Starts ...

#41. Characterisation of the expression and function ... - Agris (FAO)

The granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine able to regulate a variety of cell functions including ...

#42. GM-CSF is not essential for experimental autoimmune ...

GM -CSF functions as a hematopoietic growth factor and proinflammatory cytokine, promoting activation and tissue accumulation of monocytes, ...

#43. GM-CSF Autoantibodies and Neutrophil Dysfunction in ...

The antimicrobial functions of neutrophils are impaired in patients with pulmonary alveolar proteinosis, owing to the presence of GM-CSF ...

#44. RORgt+ ILC-derived GM-CSF protects during colitis - Science

Here we show that deficient granulocyte macrophage colony-stimulating factor (GM-. CSF) production altered mononuclear phagocyte (MNP) effector functions ...

#45. Evaluation of the effect of GM-CSF blocking on the phenotype ...

effect of GM-CSF blocking on the phenotype and function of human monocytes." (2020). Department of Neurology Faculty Papers. Paper 215.

#46. Innate Immune Modulation by GM-CSF and IL-3 in Health and ...

Finally, GM-CSF and to a lesser extent IL-3 play a critical role in experimental models of trained immunity by acting not only on bone marrow precursors but ...

#47. Mimicking Behçet's disease: GM-CSF gain of function ...

Mimicking Behçet's disease: GM-CSF gain of function mutation in a family suffering from a Behçet's disease-like disorder marked by extreme pathergy.

#48. Defective Leukocyte GM-CSF Receptor (CD116) Expression ...

Defective Leukocyte GM-CSF Receptor (CD116) Expression and Function in Inflammatory Bowel Disease. JONATHAN I. GOLDSTEIN, DOUGLAS J. KOMINSKY, ...

#49. LEADGMP ® GM-CSF (Granulocyte-Macrophage Colony ...

GM -CSF is produced by multiple cell types including activated T cells, B cells, macrophages, endothelial cells and fibroblasts upon receiving immune stimuli. GM ...

#50. Granulocyte-macrophage colony-stimulating factor increases ...

GM -CSF is vital to the maturation of macrophages and invariant natural-killer T cells and is involved in the development and function of ...

#51. Characterisation of the expression and function of ... - CiteSeerX

The granulocyte-macrophage colony-stimulating factor (GM-CSF) is a hematopoietic cytokine able to regulate a variety of cell functions including ...

#52. Clinical Use of Subcutaneous G-CSF or GM-CSF in Malignancy

[1,2] While G-CSF is relatively lineage-specific, granulocyte-macrophage colonystimulating factor (GM-CSF) functions at earlier stages of ...

#53. Human GM-CSF | Premium and research grade - MiltenyiBiotec

Background information. GM-CSF is a hematopoietic growth factor, which is essential for proliferation and development of granulocyte and monocyte/macrophage ...

#54. T Cell-Derived GM-CSF, Regulation of Expression and Function

Granulocyte-macrophage colony-stimulating factor (GM-CSF) is produced by a variety of cells and plays an important role in the inflammatory ...

#55. GM-CSF instigates a dendritic cell–T-cell inflammatory circuit ...

What factors drive development of neutrophil-mediated chronic lung disease remains largely unknown, and we sought to study the role of GM-CSF as ...

#56. GMCSF - Granulocyte-macrophage colony-stimulating factor

Q5W4T7 · Q5W4T7_CHICK · Function · Names & Taxonomy · Subcellular Location · Phenotypes & Variants · PTM/Processing · Expression · Interaction · Structure.

#57. Immune-Dependent and Independent Antitumor Activity of GM ...

The cytokine granulocyte-macrophage colony stimulating factor (GM-CSF, also known as CSF2) functions as a hematologic cell growth factor, stimulating blood stem ...

#58. Generation and utilization of a HEK-293T murine GM-CSF ...

Macrophages and dendritic cells (DCs) are innate immune cells that play a key role in defense against pathogens. In vitro cultures of bone ...

#59. GM‐CSF suppresses antioxidant signaling and drives IL‐1β ...

GM -CSF is a potent inflammatory cytokine regulating myeloid cell differentiation, hematopoiesis, and various other functions.

#60. GM-CSF Promotes Macrophage Alternative Activation after ...

GM -CSF was first described for its ability to generate granulocyte and macrophage populations from bone marrow precursor cells. ... It has become evident that GM- ...

#61. GM-CSF and stimulation of monocyte/macrophage function in ...

It was unclear why the effect of GM-CSF therapy on monocyte function persisted for several weeks after cessation of growth factor therapy.

#62. G-CSF and GM-CSF Are Different. Which One Is Better for ...

Because cytokine release syndrome is a feature of COVID-19-related ARDS, caution is needed. These same adverse effects on lung function are not reported in ...

#63. T Cell Production of GM-CSF Protects the Host during ...

GM -CSF expression is host protective in the context of TB infection. GM-CSF is expressed within human TB granulomas (13), is secreted by human ...

#64. Growth factors G-CSF and GM-CSF differentially preserve ...

granulocyte-macrophage colony-stimulating factor (GM-CSF) retarded the process of func- ... is accompanied by a progressive loss of functions, such as.

#65. CSF2 Gene - GeneCards | CSF2 Protein | CSF2 Antibody

GeneCards Symbol: CSF2; Colony Stimulating Factor 2; GMCSF; Sargramostim; GM- ... This gene plays a role in promoting tissue inflammation.

#66. GM-CSF Reporter HEK 293 Cells - InvivoGen

HEK-Blue™ GM-CSF cells allow the colorimetric detection of bioactive human granulocyte-macrophage colony-stimulating factor (GM-CSF, aka CSF2).

#67. Generation and Identification of GM-CSF Derived Alveolar-like ...

Bone marrow cells cultured with granulocyte macrophage colony stimulating factor (GM-CSF) generate a heterogeneous culture containing ...

#68. Colony stimulating factors | WEHI

There are four CSFs, called G-CSF, GM-CSF, M-CSF and IL-3. ... they are used as medicines to boost the production of white blood cells.

#69. GM-CSF (AF)Granulocyte-Macrophage Colony-Stimulating Factor ...

GM -CSF stimulates the production of neutrophilic granulocytes, macrophages ... immune system development and regulates neutrophil function during infection.

#70. GM-CSF communication conduit between lymphocytes ...

GM - CSF communication conduit between lymphocytes & myeloid cells in inflammation Dr. Burkhard Becher. 3,559 views3.5K views. Feb 3, 2021.

#71. GM-CSF, human recombinant | 4100 | BioVision, Inc.

98% Pure active Recombinant Human GM-CSF, which is a potent speciesspecific stimulator of bone marrow cells.

#72. Granulocyte Colony-Stimulating Factor G-CSF Stimulation

Granulocyte-colony stimulating factor is also known as colony-stimulating factor 3,G-CSF, GCSF, GM-CSF or Rm-GSF.

#73. Innate Lymphoid Cells in Inflammation and Immunity - CORE

Dysregulation of ILC function might result in chronic pathologies such ... IL-9, IL-4, and GM-CSF) (Moro et al., 2010; Neill et al., 2010;.

#74. GM-CSF - 中文百科知識

GM -CSF是granulocyte-macrophage colony stimulating factor的縮寫，意思是粒細胞-巨噬細胞集落 ... GM-CSF can also stimulate some functional activities in mature ...

#75. GM-CSF | Ligand page

Comment: GM-CSF as a target in inflammatory/autoimmune disease was reviewed by Hamilton (2015) [3]. COVID-19: In March 2021, results of the analysis of the ...

#76. New Antibodies - BioGenex

cell adhesion and function of epithelial cells in the epidermis. Desmoglein 1 ... GM-CSF activates effector functions of myeloid cells, thereby.

#77. Staidson testing MAb combo as potential COVID-19 therapy

GM -CSF is a hematopoietic growth factor involved in the generation ... Shutaiqing for the treatment of functional constipation, as well as a ...

#78. Savara Awarded Promising Innovative Medicine (PIM ...

Pulmonary macrophages need to be stimulated by GM-CSF to function properly, but in aPAP, GM-CSF is neutralized by antibodies against GM-CSF, ...

#79. Gradalis Announces Publication in Nature Communications ...

ENTPD1 has been identified as playing a role in numerous other solid ... which function as tumor suppressor cytokines, increased GM-CSF ...

#80. FAST - FSL - FslWiki

FAST (FMRIB's Automated Segmentation Tool) segments a 3D image of the brain into different tissue types (Grey Matter, White Matter, CSF, ...

#81. Arthur Mortha (@nkg2d1) / Twitter

Our international team reports that anti-GM-CSF autoantibodies (aGMABs) are a predictive marker for ... iNKT cells exert innate-like functions and produ.

#82. Cytokine Therapy Ppt - Los geht´s, Kinder!

These functions extend beyond the typical role for an inflammatory cytokine, ... Granulocyte-macrophage colony stimulating factor (GM-CSF) is among ...

#83. The top 10 global R&D institutes of 2021 - Fierce Biotech

Last year, Fierce Biotech reported on CAS' role in computational screening ... finding that the cytokines GM-CSF and IL-6 contribute to the ...

#84. Myeloid precursors abs auto

Recently has been become interested in role of myeloid-derived ... secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF), considering that ...

#85. AIVITA Biomedical Announces Publication of Phase 1 and ...

... SARS-CoV-2 spike protein, and then admixed with saline or 250 or 500 μg of granulocyte-macrophage colony-stimulating factor (GM-CSF).

#86. Granulocyte-macrophage colony stimulating factor (GM-CSF)

Granulocyte-macrophage colony stimulating factor (GM-CSF) is a protein which interacts with receptors on the surface of the primitive bone ...

#87. human csf - Inter Cellular Adhesion Molecule 1

Description: Recombinant human GM-CSF produced in E.coli is a single, non-glycosylated, polypeptide chain containing 127 amino acids, two pairs of disulfide ...

#88. Eosinophils in Allergy and Inflammation - 第 135 頁 - Google 圖書結果

Relative functional blocking avidity was ascertained by serial titration ... Each of these antibodies is a potent antagonist of GM - CSF in this assay ...

#89. Advances in Cancer Research - 第 353 頁 - Google 圖書結果

Adjuvants may function in many different ways; they may affect the character and ... Studies in rats show that soluble GM-CSF is a potent adjuvant for the ...

#90. Role of the IL-23/IL-17 Pathway in Chronic Immune-Mediated ...

Overall these results suggest a functional link between GM-CSF and the IL-17/IL-23 axis, opening important potential avenues for the treatment of PsA, ...

#91. Cabazitaxel Appears Active in Advanced Dedifferentiated ...

Dinutuximab Plus GM-CSF Falls Short in Recurrent Osteosarcoma Jen Smith 14 ... These cookies are necessary for the website to function and ...

#92. Kendig and Chernick's Disorders of the Respiratory Tract in ...

Loss of GM-CSF signaling also impairs neutrophil host defense functions, which together with impairment of macrophage host defense functions resulting from ...

#93. Neuroimmune Interface in Health and Diseases

GM -CSF knockout mice also showed reductions in astrogliosis, which may suggest that GM-CSF plays a role in activating astrocytes to protect cells and boost ...

#94. Icp47 foods - shoesiteformen.us

The herpesviral ICP47 inhibits TAP function, thereby suppressing an adaptive ... Among them, Amgen's T-VEC (a modified HSV-1 with expression of GM-CSF but ...

#95. The Role of Reactive Oxygen Species in Protective Immunity

Another approach is using the cytokine granulocytemacrophage colony-stimulating factor (GM-CSF) to augment NOX2 derived superoxide production by acting as ...

#96. Role of CD1- and MR1-restricted T cells in Immunity and Disease

In general, DCs are generated from peripheral blood CD14+ monocytes cultured in the presence of DC inducing cytokines, GM-CSF and IL-4.

#97. Cumulated Index Medicus - 第 32 卷 - 第 7691 頁 - Google 圖書結果

Eur Cytokine Netw 1991 May - Jun ; 2 ( 3 ) : 153-72 by GM - CSF and IL - 3 after an unrelated donor BMT for Protein kinase C plays an inhibitory role in ...

#98. Acta Neuropathologica - Commentary - KU Leuven (LIRIAS)

(7) An important unresolved problem is the role of soluble Aβ in PART. ... Ferrarese C, Ferraris A, Gibson JM, Gispert S, Hadjigeorgiou GM, Jasinska-Myga B, ...